clonal analysis meaning in English
纯系分析
Examples
- Clonal analysis in this study on the eye imaginal disc showed that in the oxt mutant clones , the ci expression was completely deleted
胚胎分析结果表明则t基因的突变会导致wg的转录和engrailed基因的表达受抑。 - Furthermore , the wing imaginal disc clonal analysis showed that in the homozygous sll mutant clones , the extracellular wg was dramatically reduced . the reduction of extracellular wg indicated that the wg signaling in the wing imaginal disc was disrupted . the reason leaded to this phenomenon is that sll encodes a paps transporter , so the disruption of the sll gene would generate the unsulfated heparan sulfate proteoglycan ( hspg ) , which most likely would lose normal function
进一步结合运用flp - frt系统和minute ~ - ，用缺损myc蛋白的表达来标记纯合的sll突变基因克隆，用minute ~ -来相对的扩大含sll突变基因的克隆，对翅成虫盘所作的克隆分析表明，在含sll突变基因的克隆中，细胞外的wg蛋白分布明显减少，这种细胞外的wg蛋白减少表明在翅成虫盘中wg信号传导受到了明显抑制。